Enzymes: HIV Protease
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F21%3A00551595" target="_blank" >RIV/61388963:_____/21:00551595 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1016/B978-0-12-819460-7.00172-9" target="_blank" >https://doi.org/10.1016/B978-0-12-819460-7.00172-9</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/B978-0-12-819460-7.00172-9" target="_blank" >10.1016/B978-0-12-819460-7.00172-9</a>
Alternative languages
Result language
angličtina
Original language name
Enzymes: HIV Protease
Original language description
HIV protease is a dimeric aspartic protease that plays a key role in viral maturation. HIV polyproteins are cleaved by HIV protease into functional proteins during the process of maturation, which enables viral progeny to infect new host cells. The indispensable role of HIV protease in the viral life cycle makes it a suitable therapeutic target. Development of inhibitors of HIV protease heralded a new era in treatment of HIV–highly effective combinations of several antiretroviral drugs with different mechanisms of action–and advanced the development of other antiviral therapies. HIV protease is an extremely well-studied enzyme and a suitable model enzyme for various studies.
Czech name
—
Czech description
—
Classification
Type
C - Chapter in a specialist book
CEP classification
—
OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Encyclopedia of Biological Chemistry
ISBN
978-0-12-819460-7
Number of pages of the result
6
Pages from-to
264-269
Number of pages of the book
785
Publisher name
Elsevier
Place of publication
Amsterdam
UT code for WoS chapter
—