2'3' cyclic dinucleotides with phosphonate bond activating the sting adaptor protein

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F21%3A00551988" target="_blank" >RIV/61388963:_____/21:00551988 - isvavai.cz</a>
Result on the web
<a href="https://worldwide.espacenet.com/publicationDetails/originalDocument?FT=D&date=20211221&DB=&locale=en_EP&CC=US&NR=11203610B2&KC=B2&ND=5" target="_blank" >https://worldwide.espacenet.com/publicationDetails/originalDocument?FT=D&date=20211221&DB=&locale=en_EP&CC=US&NR=11203610B2&KC=B2&ND=5</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
2'3' cyclic dinucleotides with phosphonate bond activating the sting adaptor protein
Original language description
The present disclosure relates to 2′3′ cyclic phosphonate dinucleotides of general formula (J), their pharmaceutically acceptable salts, their pharmaceutical composition and combinations of said substances and other medicaments or pharmaceuticals. The disclosure also relates to the use of said compounds for the treatment or prevention of diseases or conditions modifiable by STING protein modulation, such as cancer or viral, allergic and inflammatory diseases. In addition, these substances can be used as adjuvants in vaccines.
Czech name
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Czech description
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Project
<a href="/en/project/EF16_019%2F0000729" target="_blank" >EF16_019/0000729: Chemical biology for drugging undruggable targets</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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