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Solvent-controlled formation of alkali and alkali-earth-secured cucurbituril/guest trimers

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F23%3A00575698" target="_blank" >RIV/61388963:_____/23:00575698 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11310/23:10469194

  • Result on the web

    <a href="https://doi.org/10.1039/D3SC02032K" target="_blank" >https://doi.org/10.1039/D3SC02032K</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1039/d3sc02032k" target="_blank" >10.1039/d3sc02032k</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Solvent-controlled formation of alkali and alkali-earth-secured cucurbituril/guest trimers

  • Original language description

    Cucurbit[7]uril (CB[7]) encapsulates adamantyl and trimethylsilyl substituents of positively charged guests in dimethyl sulfoxide (DMSO). Unlike in water or deuterium oxide, addition of a selection of alkali and alkali-earth cations with van der Waals radii between 1.0 and 1.4 Å (Na+, K+, Ca2+, Sr2+, Ba2+ and Eu3+) to the CB[7]/guest complexes triggers their cation-mediated trimerization, a process that is very slow on the nuclear magnetic resonance (NMR) time scale. Smaller (Li+, Mg2+) or larger cations (Rb+, Cs+ or NH4+) are inert. The trimers display extensive CH-O interactions between the equatorial and pseudo-equatorial hydrogens of CB[7] and the carbonyl rim of the neighboring CB[7] unit in the trimer, and a deeply nested cation between the three interacting carbonylated CB[7] rims, a counteranion is likely perched in the shallow cavity formed by the three outer walls of CB[7] in the trimer. Remarkably, a guest must occupy the cavity of CB[7] for trimerization to take place. Using a combination of semi-empirical and density functional theory techniques in conjunction with continuum solvation models, we showed that trimerization is favored in DMSO, and not in water, because the penalty for the partial desolvation of three of the six CB[7] portals upon aggregation into a trimer is less unfavorable in DMSO compared to water.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10401 - Organic chemistry

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Chemical Science

  • ISSN

    2041-6520

  • e-ISSN

    2041-6539

  • Volume of the periodical

    14

  • Issue of the periodical within the volume

    35

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    9

  • Pages from-to

    9258-9266

  • UT code for WoS article

    001167938200001

  • EID of the result in the Scopus database

    2-s2.0-85170240590