Sulfonothioated meso-Methyl BODIPY Shows Enhanced Uncaging Efficiency and Releases H2Sn
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F23%3A00576178" target="_blank" >RIV/61388963:_____/23:00576178 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14310/23:00132247 RIV/60461373:22310/23:43927324
Result on the web
<a href="https://doi.org/10.1021/acs.orglett.3c02511" target="_blank" >https://doi.org/10.1021/acs.orglett.3c02511</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/acs.orglett.3c02511" target="_blank" >10.1021/acs.orglett.3c02511</a>
Alternative languages
Result language
angličtina
Original language name
Sulfonothioated meso-Methyl BODIPY Shows Enhanced Uncaging Efficiency and Releases H2Sn
Original language description
meso-Methyl BODIPY photocages stand out for their absorption properties and easy chromophore derivatization. However, their low uncaging efficiencies often hinder applications requiring release of protected substrates in high amounts. In this study, we demonstrate that the sulfonothioated BODIPY group photocleaves a sulfonylthio group from the meso-methyl position with a 10-fold higher quantum yield than the most efficient leaving groups studied to date. Photocleavage, observed in solution and in cells, is accompanied by the spatiotemporally controlled photorelease of H2Sn. For this reason, sulfonothioated BODIPY may be applied in cell signaling, redox homeostasis, and metabolic regulation studies.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10401 - Organic chemistry
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Organic Letters
ISSN
1523-7060
e-ISSN
1523-7052
Volume of the periodical
25
Issue of the periodical within the volume
36
Country of publishing house
US - UNITED STATES
Number of pages
5
Pages from-to
6705-6709
UT code for WoS article
001062605500001
EID of the result in the Scopus database
2-s2.0-85171393041