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Epitranscriptomic regulatory mechanisms, cardiomyocyte physiology, and nonconventional cardioprotective interventions

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F23%3A00583496" target="_blank" >RIV/61388963:_____/23:00583496 - isvavai.cz</a>

  • Alternative codes found

    RIV/67985823:_____/23:00583496

  • Result on the web

    <a href="https://onlinelibrary.wiley.com/doi/10.1111/eci.13992" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1111/eci.13992</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Epitranscriptomic regulatory mechanisms, cardiomyocyte physiology, and nonconventional cardioprotective interventions

  • Original language description

    Our study indicate that maternal diabetes and Hif1a deficiency have combinatorial effects on the development of the cardiac sympathetic nervous system. Consequently, HIF1a dysregulation may contribute to various sympathetic abnormalities underlying cardiac pathologies, including heart failure and sudden cardiac death. These findings highlight the importance of consid-ering maternal health and genetic factors in the develop-ment of adverse cardiac outcomes in offspring.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

  • OECD FORD branch

    30201 - Cardiac and Cardiovascular systems

Result continuities

  • Project

    <a href="/en/project/LX22NPO5104" target="_blank" >LX22NPO5104: National Institute for Research of Metabolic and Cardiovascular Diseases</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů