Reactivity of 2H-Azirines in Copper-Catalyzed Azide–Alkyne Cycloaddition Reactions

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F25%3A00638861" target="_blank" >RIV/61388963:_____/25:00638861 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11310/25:10512399
Result on the web
<a href="https://doi.org/10.1021/acs.orglett.5c03150" target="_blank" >https://doi.org/10.1021/acs.orglett.5c03150</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/acs.orglett.5c03150" target="_blank" >10.1021/acs.orglett.5c03150</a>

Result language
angličtina
Original language name
Reactivity of 2H-Azirines in Copper-Catalyzed Azide–Alkyne Cycloaddition Reactions
Original language description
A reaction between azide, alkyne and 2H-azirine resulted in C-C bond formation at position five of 1,2,3-triazole, instead of previously misidentified C-N bond connectivity. The reaction mechanism of this C-C bond formation on the triazole ring was fully explained by employing calibrated QM(DFT-D3) calculations. Functionalization of primary products provided substituted pyrimidine, furan or 1,3-oxazepine.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10401 - Organic chemistry

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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