Deoxyribozymes generating chemiluminescent signals
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F25%3A00645659" target="_blank" >RIV/61388963:_____/25:00645659 - isvavai.cz</a>
Result on the web
<a href="https://worldwide.espacenet.com/patent/search/family/074625815/publication/AU2022220987B2?q=AU2022220987B2" target="_blank" >https://worldwide.espacenet.com/patent/search/family/074625815/publication/AU2022220987B2?q=AU2022220987B2</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Deoxyribozymes generating chemiluminescent signals
Original language description
The present invention relates to self-phosphorylating deoxyribozymes containing or consisting of the nucleotide sequence: 5'-X1X2X3AX4X5-R1X6X7X8X9X10-bp1-helix1-R2-helix2-bp2-X11TGACX12TGGGAX13-helix3-X14-R3-3' (SEQ ID NO. 1) wherein X1 is G or T, X2 is G or T, X3 is A or C, X4 is G or T, X5 is A or T, X6 is G or T or A, X7 is A or C or G or T, X8 is A or G or T, X9 is T or C or A or G, X10 is A or T or G, X11 is G or A, X12 is T or C or G, X13 is T or G or C, X14 is G or A or C or T, R1 represents a nucleotide sequence containing 3 to 30 nucleotides, R2 represents a nucleotide sequence containing 3 to 30 nucleotides, R3 represents a nucleotide sequence containing 0 to 30 nucleotides, bp1 and bp2 are nucleotides selected from G, A, C, T, which together form a base pair, helix1, helix2, and helix3 each independently denotes a nucleotide sequence preferably containing 4 or more nucleotides, wherein helix 1, helix2, and helix3 together form a triple helical structure. The deoxyribozymes of the present invention may be used for detection of chemiluminescent substrates, or for detection of analytes (ligands) based on chemiluminescent reaction of the substrates catalyzed by the deoxyribozymes.
Czech name
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Czech description
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Classification
Type
P - Patent
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Patent/design ID
AU2022220987
Publisher
AU001 -
Publisher name
IP Australia
Place of publication
Phillip ACT
Publication country
AU - AUSTRALIA
Date of acceptance
May 22, 2025
Owner name
Ústav organické chemie a biochemie AV ČR, v. v. i.
Method of use
A - Výsledek využívá pouze poskytovatel
Usage type
A - K využití výsledku jiným subjektem je vždy nutné nabytí licence