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Switching off the endonuclease activity of type I restriction-modification enzyme CoR1241: a potential molecular motor

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F04%3A00107953" target="_blank" >RIV/61388971:_____/04:00107953 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Switching off the endonuclease activity of type I restriction-modification enzyme CoR1241: a potential molecular motor

  • Original language description

    Mutations in the endonuclease motif of HsdR subunit of restriction-modification enzyme EcoR124I, which represents a potential molecular motor, were prepared. This genetic modification resulted in the HsdR124I motor subunit not able to cleave DNA but retaining the translocation activity which can be used in nanobiotechnology.

  • Czech name

    Vypínání endonukleasové aktivity restrikčně-modifikačního enzymu typu I, EcoR124I: potenciální molekulární motor

  • Czech description

    Byly připraveny mutace v endonukleasovém motivu podjednotky HsdR restrikčně-modifikačního enzymu EcoR124I, který představuje potenciální molekulární motor. Tyto genetické modifikace vedly k podjednotce HsdR124I neschopné štěpit DNA ale se zachovanou schopností translokace, která může být využita při bionanotechnologiích.

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    EE - Microbiology, virology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2004

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    Meeting of the Federation of the European Biochemical Societies /29./

  • ISBN

  • ISSN

  • e-ISSN

  • Number of pages

    1

  • Pages from-to

    85

  • Publisher name

  • Place of publication

    Warsaw

  • Event location

    Warsaw

  • Event date

    Jun 26, 2004

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article