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Expression of apoptosis signaling genes in cancer cells exposed to HPMA copolymer-bound doxorubicin

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F04%3A00108061" target="_blank" >RIV/61388971:_____/04:00108061 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Expression of apoptosis signaling genes in cancer cells exposed to HPMA copolymer-bound doxorubicin

  • Original language description

    We compared influence of hydrolytically and enzymatically cleavable conjugates based on N-(2-hydroxypropyl)methacrylamide on proliferatin activity and expression of mRNA of genes involved in apoptotic signalling pathway. We found elevated expression of Fas and bax mRNA in cells incubated with hydrolytically cleavable conjugates.

  • Czech name

    Exprese genů pro signalizaci apoptozy u buněk vystavených účinku HPMA konjugátů doxorubicinu

  • Czech description

    Sledovali jsme vliv hydrolyticky a enzymaticky štěpitelných polymerních konjugátů na bázi N-(2-hydroxypropyl)metakrylamidu na proliferační aktivitu a expresi mRNA pro některé proteiny apoptotické signalizační kaskády. U buněk inkubovaných s hydrolytickyštěpitelným konjugátem byla zjištěna zvýšená exprese Fas a bax mRNA.

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    EE - Microbiology, virology

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2004

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    International Conference on Tumor Microenvironment:Progression, Therapy and Prevention /3./

  • ISBN

  • ISSN

  • e-ISSN

  • Number of pages

    1

  • Pages from-to

    134

  • Publisher name

    Neuveden

  • Place of publication

    Praha

  • Event location

    Praha

  • Event date

    Oct 12, 2004

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article