WT1 expression in peripheral leukocytes of patients with chronic myeloid leukemia serves for the prediction of Imatinib resistance

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F09%3A00341448" target="_blank" >RIV/61388971:_____/09:00341448 - isvavai.cz</a>

Alternative codes found

RIV/00023736:_____/09:00008299

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

WT1 expression in peripheral leukocytes of patients with chronic myeloid leukemia serves for the prediction of Imatinib resistance

Original language description

The determination of patient's resistance to a particular drug contributes to more efficient therapeutical approach. The aim of this study was to evaluate if the responsiveness of Chronic Myeloid Leukemia (CML) patients to Imatinib therapy was predictable from WT1 gene expression in peripheral blood leukocytes. To examine the resistance we implemented an in vitro cultivation of the primary cells of 48 CML patients with Imatinib

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EC - Immunology

OECD FORD branch

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Project

<a href="/en/project/NR8748" target="_blank" >NR8748: New molecular markers of residual disease in acute myeloid leukemia patients and of disease progression in myelodysplastic patients, and prediction of STI-571 responsiveness in chronic myeloid leukemia patients at molecular level.</a><br>

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Neoplasma

ISSN

0028-2685

e-ISSN

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Volume of the periodical

56

Issue of the periodical within the volume

5

Country of publishing house

SK - SLOVAKIA

Number of pages

5

Pages from-to

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UT code for WoS article

000269333200004

EID of the result in the Scopus database

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