Preclinical evaluation of linear HPMA-doxorubicin conjugates with pH-sensitive drug release: Efficacy, safety and immunomodulating activity in murine model
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F10%3A00340865" target="_blank" >RIV/61388971:_____/10:00340865 - isvavai.cz</a>
Alternative codes found
RIV/61389013:_____/10:00340865
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Preclinical evaluation of linear HPMA-doxorubicin conjugates with pH-sensitive drug release: Efficacy, safety and immunomodulating activity in murine model
Original language description
Well-defined linear conjugates of HPMA copolymer and doxorubicin bound via a pH-controlled linkage can induce complete cure of already developed murine solid tumors without significant side effects, and induce development of specific anti-tumor resistance. The HPMA-doxorubicin conjugate is a good candidate for clinical trials
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EC - Immunology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/KAN200200651" target="_blank" >KAN200200651: Nanoparticulate and supramolecular systems for targeted drug delivery</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Pharmaceutical Research
ISSN
0724-8741
e-ISSN
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Volume of the periodical
27
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
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UT code for WoS article
000272905300020
EID of the result in the Scopus database
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