Micellar and antibody-targeted polymer therapeutics
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F10%3A00349044" target="_blank" >RIV/61388971:_____/10:00349044 - isvavai.cz</a>
Alternative codes found
RIV/61389013:_____/10:00349044
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Micellar and antibody-targeted polymer therapeutics
Original language description
Synthesis, physicochemical and some biological properties of new actively targeted antibody-containing and passively targeted micellar polymer - doxorubicin conjugates were investigated. Micellar HPMA-copolymer-based pharmaceuticals were prepared by self-assembly of copolymer?doxorubicin conjugates containing hydrophobic cholesterol ligands attached to the copolymer via hydrolytically degradable spacer. Synthesis of star antibody-targeted polymer conjugates takes advantage of reduction of disulfide bridges in antibody followed by conjugation with the semitelechelic copolymer.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CD - Macromolecular chemistry
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Macromolecular Symposia
ISSN
1022-1360
e-ISSN
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Volume of the periodical
295
Issue of the periodical within the volume
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Country of publishing house
DE - GERMANY
Number of pages
12
Pages from-to
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UT code for WoS article
000288038700001
EID of the result in the Scopus database
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