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Enzymatic characterization and molecular modeling of an evolutionarily interesting fungal ?-N-acetylhexosaminidase

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F11%3A00366613" target="_blank" >RIV/61388971:_____/11:00366613 - isvavai.cz</a>

  • Alternative codes found

    RIV/67179843:_____/11:00366613

  • Result on the web

    <a href="http://dx.doi.org/10.1111/j.1742-4658.2011.08173.x" target="_blank" >http://dx.doi.org/10.1111/j.1742-4658.2011.08173.x</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1111/j.1742-4658.2011.08173.x" target="_blank" >10.1111/j.1742-4658.2011.08173.x</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Enzymatic characterization and molecular modeling of an evolutionarily interesting fungal ?-N-acetylhexosaminidase

  • Original language description

    Fungal b-N-acetylhexosaminidases are inducible extracellular enzymes with many biotechnological applications. The enzyme from Penicillium oxalicum has unique enzymatic properties despite its close evolutionary relationship with other fungal hexosaminidases. It has high GalNAcase activity, tolerates substrates with the modified N-acyl group better and has some other unusual catalytic properties. In order to understand these features, we performed isolation, biochemical and enzymological characterization,molecular cloning and molecular modelling. The native enzyme is composed of two catalytic units (65 kDa each) and two propeptides (15 kDa each), yielding a molecular weight of 160 kDa

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CE - Biochemistry

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    FEBS Journal

  • ISSN

    1742-464X

  • e-ISSN

  • Volume of the periodical

    278

  • Issue of the periodical within the volume

    14

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    16

  • Pages from-to

    2469-2484

  • UT code for WoS article

    000292932700007

  • EID of the result in the Scopus database