Control of cell division in Streptococcus pneumoniae by the conserved Ser/Thr protein kinase StkP
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F12%3A00378667" target="_blank" >RIV/61388971:_____/12:00378667 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1073/pnas.1119172109" target="_blank" >http://dx.doi.org/10.1073/pnas.1119172109</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1073/pnas.1119172109" target="_blank" >10.1073/pnas.1119172109</a>
Alternative languages
Result language
angličtina
Original language name
Control of cell division in Streptococcus pneumoniae by the conserved Ser/Thr protein kinase StkP
Original language description
How the human pathogen Streptococcus pneumoniae coordinates cell-wall synthesis during growth and division to achieve its characteristic oval shape is poorly understood. The conserved eukaryotic-type Ser/Thr kinase of S. pneumoniae, StkP, previously wasreported to phosphorylate the cell-division protein DivIVA. Consistent with a role in cell division, GFP-StkP and its cognate phosphatase, GFP-PhpP, both localize to the division site. StkP localization depends on its penicillin-binding protein and Ser/Thr-associated domains that likely sense uncross-linked peptidoglycan, because StkP and PhpP delocalize in the presence of antibiotics that target the latest stages of cell-wall biosynthesis and in cells that have stopped dividing
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EE - Microbiology, virology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Proceedings of the National Academy of Sciences of the United States of America
ISSN
0027-8424
e-ISSN
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Volume of the periodical
109
Issue of the periodical within the volume
15
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
905-913
UT code for WoS article
000302533500007
EID of the result in the Scopus database
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