Vital mitochondrial functions show profound changes during yeast culture ageing

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F13%3A00396040" target="_blank" >RIV/61388971:_____/13:00396040 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1111/1567-1364.12001" target="_blank" >http://dx.doi.org/10.1111/1567-1364.12001</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/1567-1364.12001" target="_blank" >10.1111/1567-1364.12001</a>

Result language

angličtina

Original language name

Vital mitochondrial functions show profound changes during yeast culture ageing

Original language description

During a 10-day culture ageing, cells of the wild-type Saccharomyces cerevisiae strain JC 482 retain their viability, while mitochondrial function and morphology change. Cell routine and uncoupled respiration rates increase to a maximum on day 4 and thendecline to near zero. The decline, which occurs also in mitochondria isolated from cells of different age, is not due to increasing proportion of petites. Rhodamine 123 fluorescence intensity reporting on mitochondrial membrane potential appears to dropslightly for 4 days and then more sharply at the time when respiration rate also decreases. The MitoTracker Green fluorescent signal related to the mitochondrial content per cell also decreases. The branched tubular mitochondrial network of 1-day-old cells dissolves into short fragments; during the first 4 days, this fragmentation is associated with increasing function of mitochondria, while later on, it accompanies functional decline, which is also indicated by the decreasing ratio of

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EE - Microbiology, virology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

FEMS Yeast Research

ISSN

1567-1356

e-ISSN

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Volume of the periodical

13

Issue of the periodical within the volume

1

Country of publishing house

US - UNITED STATES

Number of pages

9

Pages from-to

7-15

UT code for WoS article

000313722000003

EID of the result in the Scopus database

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