Chemoenzymatic Synthesis of beta-D-Glucosides using Cellobiose Phosphorylase from Clostridium thermocellum

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F15%3A00445823" target="_blank" >RIV/61388971:_____/15:00445823 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1002/adsc.201500077" target="_blank" >http://dx.doi.org/10.1002/adsc.201500077</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/adsc.201500077" target="_blank" >10.1002/adsc.201500077</a>

Result language

angličtina

Original language name

Chemoenzymatic Synthesis of beta-D-Glucosides using Cellobiose Phosphorylase from Clostridium thermocellum

Original language description

Over the past decade, disaccharide phosphorylases have been successfully applied for the synthesis of numerous a-glucosides. In contrast, much less research has been done with respect to the production of beta-glucosides. Although cellobiose phosphorylase was already successfully used for the synthesis of various disaccharides and branched trisaccharides, its glycosylation potential towards small organic compounds has not been explored to date. Unfortunately, disaccharide phosphorylases typically have avery low affinity for non-carbohydrate acceptors, which urges the addition of solvents. The ionic liquid AMMOENG (TM) 101 and ethyl acetate were identified as the most promising solvents, allowing the synthesis of various beta-glucosides. Next to hexyl,heptyl, octyl, nonyl, decyl and undecyl beta-D-glucopyranosides, also the formation of vanillyl 4-O-beta-D-glucopyranoside, 2-phenylethyl beta-D-glucopyranoside, beta-citronellyl beta-D-glucopyranoside and 1-O-beta-D-glucopyranosyl hydro

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CE - Biochemistry

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Advanced Synthesis & Catalysis

ISSN

1615-4150

e-ISSN

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Volume of the periodical

357

Issue of the periodical within the volume

8

Country of publishing house

DE - GERMANY

Number of pages

9

Pages from-to

1961-1969

UT code for WoS article

000355235700035

EID of the result in the Scopus database

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