Gnotobiology and the study of complex interactions between the intestinal microbiota, probiotics and the host

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F15%3A00457565" target="_blank" >RIV/61388971:_____/15:00457565 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/B978-0-12-415847-4.00008-2" target="_blank" >http://dx.doi.org/10.1016/B978-0-12-415847-4.00008-2</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/B978-0-12-415847-4.00008-2" target="_blank" >10.1016/B978-0-12-415847-4.00008-2</a>

Result language
angličtina
Original language name
Gnotobiology and the study of complex interactions between the intestinal microbiota, probiotics and the host
Original language description
GGnotobiology technology for the breeding of experimental mice originated in the first half of the twentieth century. Earlier studies conducted in germ-free animals revealed the importance of the microbiota in the development of the immune system, gut morphology, and metabolism. These seminal studies have been confirmed and complemented by recent work that exploits the use of modern gnotobiotic technology as well as the combination of high-throughput molecular techniques to study the composition and metabolic capacity of the intestinal microbiota. From a historical perspective, this chapter discusses the evolution of theory concerning complex host-microbiota interactions and probiotics species. It also reviews the current evidence for a role of maladaptive interactions in the development of disease within and beyond the gastrointestinal tract.
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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