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The method of surface modification for the purpose of enrichment of phosphorylated peptides for analysis by desorption/ionization mass spectrometry techniques

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F15%3A00465769" target="_blank" >RIV/61388971:_____/15:00465769 - isvavai.cz</a>

  • Result on the web

    <a href="https://worldwide.espacenet.com/publicationDetails/originalDocument?FT=D&date=20151125&DB=&locale=en_EP&CC=EP&NR=2652769B1&KC=B1&ND=4" target="_blank" >https://worldwide.espacenet.com/publicationDetails/originalDocument?FT=D&date=20151125&DB=&locale=en_EP&CC=EP&NR=2652769B1&KC=B1&ND=4</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    The method of surface modification for the purpose of enrichment of phosphorylated peptides for analysis by desorption/ionization mass spectrometry techniques

  • Original language description

    The present invention relates to a method of making modification of solid substrates for efficient surface preconcentration of phosphorylated peptides from complex peptide mixtures prior detection based on desorption-ionization mass spectrometry. The subject of the protection is a method of modifying surfaces used as substrates for desorption-ionization mass spectrometry. The method according to the present invention is based on electronebulization (electrospraying) of a solution of organometallic compounds of the group 4B elements, and namely zirconium, hafnium and titanium. The charged elecrospray thus obtained is dried in real time by passage through a heated space and impinges onto a surface to which it fixedly binds in the form of oxide.; The surface modified in such a manner can then be used for preconcentration of phosphorylated peptides from peptide mixtures with subsequent analysis using desorption-ionization mass spectrometry.

  • Czech name

  • Czech description

Classification

  • Type

    P - Patent

  • CEP classification

    EE - Microbiology, virology

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Patent/design ID

    EP2652769

  • Publisher

    EPO_1 -

  • Publisher name

    European Patent Office

  • Place of publication

    Munich, The Hague, Berlin, Vienna, Brussels

  • Publication country

  • Date of acceptance

    Nov 25, 2015

  • Owner name

    Mikrobiologický ústav AV ČR, v. v. i.

  • Method of use

    A - Výsledek využívá pouze poskytovatel

  • Usage type

    A - K využití výsledku jiným subjektem je vždy nutné nabytí licence