Yeast cell differentiation: Lessons from pathogenic and non-pathogenic yeasts
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F16%3A00466366" target="_blank" >RIV/61388971:_____/16:00466366 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11310/16:10325328
Result on the web
<a href="http://dx.doi.org/10.1016/j.semcdb.2016.04.006" target="_blank" >http://dx.doi.org/10.1016/j.semcdb.2016.04.006</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.semcdb.2016.04.006" target="_blank" >10.1016/j.semcdb.2016.04.006</a>
Alternative languages
Result language
angličtina
Original language name
Yeast cell differentiation: Lessons from pathogenic and non-pathogenic yeasts
Original language description
Yeasts, historically considered to be single-cell organisms, are able to activate different differentiation processes. Individual yeast cells can change their life-styles by processes of phenotypic switching such as the switch from yeast-shaped cells to filamentous cells (pseudohyphae or true hyphae) and the transition among opaque, white and gray cell-types. Yeasts can also create organized multicellular structures such as colonies and biofilms, and the latter are often observed as contaminants on surfaces in industry and medical care and are formed during infections of the human body. Multicellular structures are formed mostly of stationary-phase or slow-growing cells that diversify into specific cell subpopulations that have unique metabolic properties and can fulfill specific tasks. In addition to the development of multiple protective mechanisms, processes of metabolic reprogramming that reflect a changed environment help differentiated individual cells and/or community cell constituents to survive harmful environmental attacks and/or to escape the host immune system. This review aims to provide an overview of differentiation processes so far identified in individual yeast cells as well as in multicellular communities of yeast pathogens of the Candida and Cryptococcus spp. and the Candida albicans close relative, Saccharomyces cerevisiae. Molecular mechanisms and extracellular signals potentially involved in differentiation processes are also briefly mentioned.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EE - Microbiology, virology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Seminars in Cell & Developmental Biology
ISSN
1084-9521
e-ISSN
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Volume of the periodical
57
Issue of the periodical within the volume
SEP
Country of publishing house
GB - UNITED KINGDOM
Number of pages
10
Pages from-to
110-119
UT code for WoS article
000381010500015
EID of the result in the Scopus database
2-s2.0-84964573599