Successful Posaconazole Therapy of Disseminated Alternariosis due to Alternaria infectoria in a Heart Transplant Recipient

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F17%3A00474242" target="_blank" >RIV/61388971:_____/17:00474242 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/17:10371434 RIV/00216208:11310/17:10371434 RIV/00023001:_____/17:00075928 RIV/00064190:_____/17:N0000018 RIV/61989592:15110/17:73585912

Result on the web

<a href="http://dx.doi.org/10.1007/s11046-016-0094-4" target="_blank" >http://dx.doi.org/10.1007/s11046-016-0094-4</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s11046-016-0094-4" target="_blank" >10.1007/s11046-016-0094-4</a>

Result language

angličtina

Original language name

Successful Posaconazole Therapy of Disseminated Alternariosis due to Alternaria infectoria in a Heart Transplant Recipient

Original language description

We report a case of phaeohyphomycosis caused by Alternaria infectoria in a 61-year-old heart transplant recipient with multiple skin lesions and pulmonary infiltrates. The infection spread via the haematogenous route from the primary cutaneous lesions into the lungs. The diagnosis was based on the histopathological examination, direct microscopy, skin lesion cultures and detection of Alternaria DNA in the bronchoalveolar lavage fluid using molecular methods. The treatment consisted of a combination of surgical excision and systemic antifungal therapy. Voriconazole was the first agent used but had a weak effect. Posaconazole was subsequently used to achieve a successful response. The isolate was identified as A. infectoria by sequencing of the rDNA ITS region and the partial beta-tubulin gene.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10606 - Microbiology

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Mycopathologia

ISSN

0301-486X

e-ISSN

—

Volume of the periodical

182

Issue of the periodical within the volume

3-4

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

7

Pages from-to

297-303

UT code for WoS article

000397206000003

EID of the result in the Scopus database

2-s2.0-84995791211