Polyphasic data support the splitting of Aspergillus candidus into two species, proposal of Aspergillus dobrogensis sp nov.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F18%3A00494189" target="_blank" >RIV/61388971:_____/18:00494189 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11310/18:10388186

Result on the web

<a href="http://dx.doi.org/10.1099/ijsem.0.002583" target="_blank" >http://dx.doi.org/10.1099/ijsem.0.002583</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1099/ijsem.0.002583" target="_blank" >10.1099/ijsem.0.002583</a>

Result language

angličtina

Original language name

Polyphasic data support the splitting of Aspergillus candidus into two species, proposal of Aspergillus dobrogensis sp nov.

Original language description

Aspergillus candidus is a species frequently isolated from stored grain, food, indoor environments, soil and occasionally also from clinical material. Recent bioprospecting studies highlighted the potential of using A. candidus and its relatives in various industrial sectors as a result of their significant production of enzymes and bioactive compounds. A high genetic variability was observed among A. candidus isolates originating from various European countries and the USA, that were mostly isolated from indoor environments, caves and clinical material. The A. candidus sensu lato isolates were characterized by DNA sequencing of four genetic loci, and agreement between molecular species delimitation results, morphological characters and exometabolite spectra were studied. Classical phylogenetic methods (maximum likelihood, Bayesian inference) and species delimitation methods based on the multispecies coalescent model supported recognition of up to three species in A. candidus sensu lato. After evaluation of phenotypic data, a broader species concept was adopted, and only one new species, Aspergillus dobrogensis, was proposed. This species is represented by 22 strains originating from seven countries (ex-type strain CCF 4651(T) = NRRL 62821(T) = IBT 32697(T) = CBS 143370(T)) and its differentiation from A. candidus is relevant for bioprospecting studies because these species have different exometabolite profiles. Evaluation of the antifungal susceptibility of section Candidi members to six antifungals using the reference EUCAST method showed that all species have low minimum inhibitory concentrations for all tested antifungals. These results suggest applicability of a wide spectrum of antifungal agents for treatment of infections caused by species from section Candidi.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10606 - Microbiology

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International Journal of Systematic and Evolutionary Microbiology

ISSN

1466-5026

e-ISSN

—

Volume of the periodical

68

Issue of the periodical within the volume

4

Country of publishing house

GB - UNITED KINGDOM

Number of pages

17

Pages from-to

995-1011

UT code for WoS article

000433170100004

EID of the result in the Scopus database

2-s2.0-85044924162