Fungal Keratitis Caused by Colletotrichum dematium: Case Study and Review

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F19%3A00517770" target="_blank" >RIV/61388971:_____/19:00517770 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11150/19:10399948 RIV/00216208:11310/19:10399948 RIV/00179906:_____/19:10399948
Result on the web
<a href="https://link.springer.com/article/10.1007%2Fs11046-019-00335-w" target="_blank" >https://link.springer.com/article/10.1007%2Fs11046-019-00335-w</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s11046-019-00335-w" target="_blank" >10.1007/s11046-019-00335-w</a>

Result language
angličtina
Original language name
Fungal Keratitis Caused by Colletotrichum dematium: Case Study and Review
Original language description
Colletotrichum species are known as important pathogens of plants with an impact on crop production. Some of these species are also known as a cause of rare ophthalmic infections in humans. A case of keratitis caused by Colletotrichum dematium after corneal trauma in a 56-year-old woman is presented. Infection was diagnosed based on positive microscopy and culture. The fungal isolate was identified by morphological characteristics and DNA sequencing of the ITS rDNA region, -tubulin (tub2) and glyceraldehyde-3-phosphate dehydrogenase (gapdh) genes. The patient responded well to topical therapy with amphotericin B combined with intravenous amphotericin B but improvement was associated with the corneal collagen cross-linking. The review of the literature revealed another 13 cases of C. dematium keratitis, all but one patient having at least one keratitis risk factor in their history. Almost all patients (n=12) were treated with topical polyene antibiotics (natamycin or amphotericin B), improvement and cure were achieved in eight of them.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10606 - Microbiology

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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