Adenylate Cyclase Toxin Tinkering With Monocyte-Macrophage Differentiation

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F20%3A00535242" target="_blank" >RIV/61388971:_____/20:00535242 - isvavai.cz</a>
Result on the web
<a href="https://www.frontiersin.org/articles/10.3389/fimmu.2020.02181/full" target="_blank" >https://www.frontiersin.org/articles/10.3389/fimmu.2020.02181/full</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3389/fimmu.2020.02181" target="_blank" >10.3389/fimmu.2020.02181</a>

Result language
angličtina
Original language name
Adenylate Cyclase Toxin Tinkering With Monocyte-Macrophage Differentiation
Original language description
Circulating inflammatory monocytes are attracted to infected mucosa and differentiate into macrophage or dendritic cells endowed with enhanced bactericidal and antigen presenting capacities. In this brief Perspective we discuss the newly emerging insight into how the cAMP signaling capacity ofBordetella pertussisadenylate cyclase toxin manipulates the differentiation of monocytes and trigger dedifferentiation of the alveolar macrophages to facilitate bacterial colonization of human airways.
Czech name
—
Czech description
—

Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30102 - Immunology

Project
<a href="/en/project/GX19-27630X" target="_blank" >GX19-27630X: Concerted toxin action in Bordetella pertussis virulence</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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