Immunomodulatory Components of Human Colostrum and Milk
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F20%3A00552173" target="_blank" >RIV/61388971:_____/20:00552173 - isvavai.cz</a>
Alternative codes found
RIV/68378041:_____/20:00560382
Result on the web
<a href="http://dx.doi.org/10.1159/000505068" target="_blank" >http://dx.doi.org/10.1159/000505068</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1159/000505068" target="_blank" >10.1159/000505068</a>
Alternative languages
Result language
angličtina
Original language name
Immunomodulatory Components of Human Colostrum and Milk
Original language description
Human milk is a unique and complex secretion differing from lacteal secretions of other species. Besides nutrition, it provides protection during the newborn's adaption to the extrauterine environment and reduces the morbidity and mortality caused by both infectious and noninfectious diseases. Its components act directly against infectious agents, but they also accelerate the newborn's immune system development, increasing its capacity for defense and reducing the risk of allergy and other immune-related diseases. Cytokines show the most refined immunomodulatory effects, but oligosaccharides, hormones, and other components affect the newborn's immunity as well. Furthermore, milk components substantially affect the microbial colonization of infant mucosa, which substantially influences the development of all parts of the immune system. All these components act primarily locally, on the mucosal membranes, preventing the penetration of microbes and other antigenic components into the circulation thus ensuring effective defense without the damaging inflammation. Human lacteal secretions contain a number of live cells. Although there are no major differences in the cytokine production between allergic and healthy mothers, they are able to respond to multiple stimuli. By increasing happiness, boosting protective immunity, and decreasing the risk of breast cancer, breastfeeding may have multiple benefits for the mother as well. (C) 2020 Nestle Nutrition Institute, Switzerland/S. Karger AG, Basel
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
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OECD FORD branch
30102 - Immunology
Result continuities
Project
<a href="/en/project/GA17-11275S" target="_blank" >GA17-11275S: Innate-glycan-mediated and specific IgA-dependent protection in bacterial intestinal infection of experimental animals</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
Milk, Mucosal Immunity and the Microbiome: Impact on the Neonate
ISBN
978-3-318-06684-5
ISSN
—
e-ISSN
—
Number of pages
10
Pages from-to
38-47
Publisher name
KARGER
Place of publication
Basel
Event location
Lausanne
Event date
Sep 23, 2019
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
000659299600004