NMR Structure Elucidation of Naphthoquinones from Quambalaria cyanescens
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F21%3A00538938" target="_blank" >RIV/61388971:_____/21:00538938 - isvavai.cz</a>
Alternative codes found
RIV/61388963:_____/21:00538938 RIV/00216208:11310/21:10430105
Result on the web
<a href="https://doi.org/10.1021/acs.jnatprod.0c00930" target="_blank" >https://doi.org/10.1021/acs.jnatprod.0c00930</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/acs.jnatprod.0c00930" target="_blank" >10.1021/acs.jnatprod.0c00930</a>
Alternative languages
Result language
angličtina
Original language name
NMR Structure Elucidation of Naphthoquinones from Quambalaria cyanescens
Original language description
Naphthoquinones isolated from Quambalaria cyanescens (quambalarines) are natural pigments possessing significant cytotoxic and antimicrobial properties. Determining the structure of naphthoquinone compounds is important for the understanding of their biological activities and the informed synthesis of related analogues. Identifying quambalarines is challenging, because they contain a hydroxylated naphthoquinone scaffold and have limited solubility. Here, we report a detailed structural study of quambalarine derivatives, which form strong intramolecular hydrogen bonds (IMHBs) that enable the formation of several tautomers, these tautomers may complicate structural investigation due to their fast interconversion. To investigate tautomeric equilibria and identify new quambalarines, we complemented the experimental NMR spectroscopy data with density functional theory (DFT) calculations.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10401 - Organic chemistry
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Natural Products
ISSN
0163-3864
e-ISSN
1520-6025
Volume of the periodical
84
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
46-55
UT code for WoS article
000613247300006
EID of the result in the Scopus database
2-s2.0-85098755178