Advanced glycosidases as ingenious biosynthetic instruments
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F21%3A00546051" target="_blank" >RIV/61388971:_____/21:00546051 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11310/21:10430272
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0734975021000392?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0734975021000392?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.biotechadv.2021.107733" target="_blank" >10.1016/j.biotechadv.2021.107733</a>
Alternative languages
Result language
angličtina
Original language name
Advanced glycosidases as ingenious biosynthetic instruments
Original language description
Until recently, glycosidases, naturally hydrolyzing carbohydrate-active enzymes, have found few synthetic applications in industry, being primarily used for cleaving unwanted carbohydrates. With the establishment of glycosynthase and transglycosidase technology by genetic engineering, the view of glycosidases as industrial biotechnology tools has started to change. Their easy production, affordability, robustness, and substrate versatility, added to the possibility of controlling undesired side hydrolysis by enzyme engineering, have made glycosidases competitive synthetic tools. Current promising applications of engineered glycosidases include the production of well-defined chitooligomers, precious galactooligosaccharides or specialty chemicals such as glycosylated flavonoids. Other synthetic pathways leading to human milk oligosaccharides or remodeled antibodies are on the horizon. This work provides an overview of the synthetic achievements to date for glycosidases, emphasizing the latest trends and outlining possible developments in the field.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biotechnology Advances
ISSN
0734-9750
e-ISSN
1873-1899
Volume of the periodical
49
Issue of the periodical within the volume
JUL-AUG
Country of publishing house
US - UNITED STATES
Number of pages
27
Pages from-to
107733
UT code for WoS article
000663421300011
EID of the result in the Scopus database
2-s2.0-85103794506