Immunomodulatory Effects ofAllium sativum L. and its Constituents against Viral Infections and Metabolic Diseases
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F22%3A00555095" target="_blank" >RIV/61388971:_____/22:00555095 - isvavai.cz</a>
Result on the web
<a href="https://www.eurekaselect.com/article/119000" target="_blank" >https://www.eurekaselect.com/article/119000</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2174/1568026621666211122163156" target="_blank" >10.2174/1568026621666211122163156</a>
Alternative languages
Result language
angličtina
Original language name
Immunomodulatory Effects ofAllium sativum L. and its Constituents against Viral Infections and Metabolic Diseases
Original language description
Background: Allium sativum L., or garlic, is one of the most studied plants worldwide within the field of traditional medicine. Current interests lie in the potential use of garlic as a preventive measure and adjuvant treatment for viral infections, e.g., SARS-CoV-2. Even though it cannot be presented as a single treatment, its beneficial effects are beyond doubt. The World Health Organization has deemed it an essential part of any balanced diet with immunomodulatory properties. Objective: The aim of the study was to review the literature on the effects of garlic compounds and preparations on immunomodulation and viral infection management, with emphasis on SARS-CoV-2. Methods: Exhaustive literature search has been carried out on electronic databases. Conclusion: Garlic is a fundamental part of a well-balanced diet which helps maintain general good health. The reported information regarding garlic's ability to beneficially modulate inflammation and the immune system is encouraging. Nonetheless, more efforts must be made to understand the actual medicinal properties and mechanisms of action of the compounds found in this plant to inhibit or diminish viral infections, particularly SARS-CoV-2. Based on our findings, we propose a series of innovative strategies to achieve such a challenge in the near future.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10606 - Microbiology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Current Topics in Medicinal Chemistry
ISSN
1568-0266
e-ISSN
1873-4294
Volume of the periodical
22
Issue of the periodical within the volume
2
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
23
Pages from-to
109-131
UT code for WoS article
000755024200004
EID of the result in the Scopus database
2-s2.0-85125554216