Diagnosis of Aspergillosis in Horses
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F23%3A00571794" target="_blank" >RIV/61388971:_____/23:00571794 - isvavai.cz</a>
Alternative codes found
RIV/61988987:17110/23:A2402N25 RIV/61989592:15310/23:73621633 RIV/71009396:_____/23:N0000024
Result on the web
<a href="https://www.mdpi.com/2309-608X/9/2/161" target="_blank" >https://www.mdpi.com/2309-608X/9/2/161</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/jof9020161" target="_blank" >10.3390/jof9020161</a>
Alternative languages
Result language
angličtina
Original language name
Diagnosis of Aspergillosis in Horses
Original language description
Invasive pulmonary aspergillosis (IPA) may be a rare cause of granulomatous pneumonia in horses. The mortality of IPA is almost 100%, direct diagnostic tools in horses are needed. Bronchoalveolar lavage fluid (BALF) and serum samples were collected from 18 horses, including individuals suffering from IPA (n = 1), equine asthma (EA, n = 12), and 5 healthy controls. Serum samples were collected from another 6 healthy controls. Samples of BALF (n = 18) were analyzed for Aspergillus spp. DNA, fungal galactomannan (GM), ferricrocin (Fc), triacetylfusarinin C (TafC), and gliotoxin (Gtx). Analysis of 24 serum samples for (1,3)-beta-D-glucan (BDG) and GM was performed. Median serum BDG levels were 131 pg/mL in controls and 1142 pg/mL in IPA. Similar trends were observed in BALF samples for GM (Area under the Curve (AUC) = 0.941) and DNA (AUC = 0.941). The fungal secondary metabolite Gtx was detected in IPA BALF and lung tissue samples (86 ng/mL and 2.17 ng/mg, AUC = 1).
Czech name
—
Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10606 - Microbiology
Result continuities
Project
<a href="/en/project/GA21-17044S" target="_blank" >GA21-17044S: Next-generation infection diagnostics</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Fungi
ISSN
2309-608X
e-ISSN
2309-608X
Volume of the periodical
9
Issue of the periodical within the volume
2
Country of publishing house
CH - SWITZERLAND
Number of pages
13
Pages from-to
161
UT code for WoS article
000940566000001
EID of the result in the Scopus database
2-s2.0-85148868669