Commissioning the digital mass-filter/ion-trap module for the MS SPIDOC prototype
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F23%3A00581604" target="_blank" >RIV/61388971:_____/23:00581604 - isvavai.cz</a>
Result on the web
<a href="https://iopscience.iop.org/article/10.1088/1748-0221/18/10/P10021" target="_blank" >https://iopscience.iop.org/article/10.1088/1748-0221/18/10/P10021</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1088/1748-0221/18/10/P10021" target="_blank" >10.1088/1748-0221/18/10/P10021</a>
Alternative languages
Result language
angličtina
Original language name
Commissioning the digital mass-filter/ion-trap module for the MS SPIDOC prototype
Original language description
The combination of a linear quadrupole ion-filter and linear Paul trap operated with a rectangular guiding field for the filtering and accumulation of ions within the Mass Spectrometry for Single Particle Imaging of Dipole Oriented protein Complexes (MS SPIDOC) prototype [T. Kierspel et al., Anal. Bioanal. Chem., published online] is characterized. Using cationic caesium-iodide clusters, the ion-separation performance, ion accumulation, cooling, and ejection via in-trap pin electrodes is evaluated. Furthermore, proof-of-principle measurements are performed with 64 kDa multiply-charged non-covalent protein complexes of human hemoglobin and 804 kDa non-covalent complex of GroEL, to demonstrate that the module meets the criteria to handle high-mass ions which are the main objective of the MS SPIDOC project. The setup's performance is found to be in line with previous results from ion-trajectory simulations [F. Simke et al., Int. J. Mass Spectrom. 473 (2022) 116779].
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10406 - Analytical chemistry
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Instrumentation
ISSN
1748-0221
e-ISSN
1748-0221
Volume of the periodical
18
Issue of the periodical within the volume
10
Country of publishing house
US - UNITED STATES
Number of pages
18
Pages from-to
P10021
UT code for WoS article
001117781700010
EID of the result in the Scopus database
2-s2.0-85175969838