From ultrafast laser-generated radiation to clinical impact: a roadmap for radiobiology and cancer research at the extreme light infrastructure (ELI)
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F25%3A00637983" target="_blank" >RIV/61388971:_____/25:00637983 - isvavai.cz</a>
Alternative codes found
RIV/61389005:_____/25:00637983 RIV/10974938:_____/25:25_96_01
Result on the web
<a href="https://link.springer.com/article/10.1140/epjp/s13360-025-06662-w" target="_blank" >https://link.springer.com/article/10.1140/epjp/s13360-025-06662-w</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1140/epjp/s13360-025-06662-w" target="_blank" >10.1140/epjp/s13360-025-06662-w</a>
Alternative languages
Result language
angličtina
Original language name
From ultrafast laser-generated radiation to clinical impact: a roadmap for radiobiology and cancer research at the extreme light infrastructure (ELI)
Original language description
The extreme light infrastructure (ELI) is emerging as a state-of-the-art facility providing international users with open access to ultrashort laser-driven particle bunches, ranging from a few femtoseconds to a few nanoseconds, for advanced radiobiology studies. ELI offers femtosecond-class laser pulses and ultrafast ionizing radiation characterized by extremely high instantaneous dose rates (107-1012 Gy/s). The versatility of ELI's cutting-edge technologies enables the generation of high repetition rate (1 Hz-1 kHz) secondary sources (protons, ions, electrons, and neutrons) with energies from a few MeV to several hundred MeV, achieved over sub-millimetre to millimetre-scale acceleration lengths, along with fundamental research in the field of ultrahigh intensity laser-matter interaction based on the use of the highest peak power laser pulses available worldwide. Harnessing these laser-driven particle sources for radiobiology and medical research demands a coordinated international effort, with a strong focus on advancing scientific instrumentation and refining experimental methodologies to support progress in ultrafast laser-driven radiation biology. This roadmap underscores the need for systematically designed experiments across ELI facilities, supported by preparatory research at users' home laboratories, alongside the ongoing development of instrumentation and infrastructure. These efforts are critical to rigorously assess and validate the therapeutic potential of these novel sources, paving the way for a transformative shift in radiation biology and medicine.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30102 - Immunology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
European Physical Journal Plus
ISSN
2190-5444
e-ISSN
2190-5444
Volume of the periodical
140
Issue of the periodical within the volume
8
Country of publishing house
DE - GERMANY
Number of pages
11
Pages from-to
730
UT code for WoS article
001543673700002
EID of the result in the Scopus database
2-s2.0-105012444111