Cutaneous histoplasmosis in a roadkill European badger (Meles meles), Czech Republic
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F25%3A00643056" target="_blank" >RIV/61388971:_____/25:00643056 - isvavai.cz</a>
Alternative codes found
RIV/62157124:16170/25:43882409 RIV/62157124:16270/25:43882409 RIV/62157124:16810/25:43882409
Result on the web
<a href="https://actavet.vfu.cz/94/3/0187/" target="_blank" >https://actavet.vfu.cz/94/3/0187/</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2754/avb202594030187" target="_blank" >10.2754/avb202594030187</a>
Alternative languages
Result language
angličtina
Original language name
Cutaneous histoplasmosis in a roadkill European badger (Meles meles), Czech Republic
Original language description
Histoplasmosis is caused by a thermally dimorphic ascomycete fungus, Histoplasma capsulatum. Europe has long been considered a non-endemic area for histoplasmosis, however, in recent decades, sporadic cases of histoplasmosis have been confirmed in the European badger (Meles meles) in Austria, Denmark, Germany and Switzerland. In 2014, an adult male badger carcass was found on a highway on the outskirts of the city of Brno (Southern Moravia, Czech Republic). A gross pathological examination revealed a good overall body condition prior to receiving multiple traumatic injuries from a car impact. However, multiple irregular nodular lesions measuring up to 5 cm in diameter were observed on the skin of the ventral part of the body and the thoracic limbs. Histopathology revealed a granulomatous inflammatory reaction in the lesions, with abundant macrophages multifocally forming large multinucleated giant cells, lymphocytes, plasma cells and scarce granulocytes. The macrophages contained oval to spherical 2.5-3.0 mu m yeast-like structures in the cytoplasm. These stained mildly to moderately with haematoxylin and eosin and well with periodic acid Schiff, revealing a small central nucleus surrounded by a clear zone. Other organs showed no macroscopic or microscopic pathology. The internal transcribed spacer rDNA sequence from the skin was identical to a sequence previously detected in a H. capsulatum-infected badger in Germany. This case report detailing cutaneous histoplasmosis in a European badger marks the first documentation of H. capsulatum in the Czech Republic and emphasises the potential for early detection of new and emerging pathogens through wildlife disease monitoring.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
40301 - Veterinary science
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Acta veterinaria Brno
ISSN
0001-7213
e-ISSN
1801-7576
Volume of the periodical
94
Issue of the periodical within the volume
3
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
6
Pages from-to
187-192
UT code for WoS article
001600618100003
EID of the result in the Scopus database
2-s2.0-105020306255