Graphene oxide nanoparticle attachment and its toxicity on living lung epithelial cells

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388980%3A_____%2F15%3A00445961" target="_blank" >RIV/61388980:_____/15:00445961 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1039/c5ra09351a" target="_blank" >http://dx.doi.org/10.1039/c5ra09351a</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1039/c5ra09351a" target="_blank" >10.1039/c5ra09351a</a>

Result language

angličtina

Original language name

Graphene oxide nanoparticle attachment and its toxicity on living lung epithelial cells

Original language description

Since its discovery, graphene and its oxidized form, graphene oxide (GO), have attracted interest in a wide range of technical applications. Concerns about their potential toxicity calls for scrutinized studies, but hitherto conflicting results have beenreported which partly may be due to variations of synthesis and exposure procedures. Here we report on the attachment and toxicity of contamination-free graphene oxide nanoparticles (GONP) in living lung epithelial cells. The synthesis of chemically pure GONP was made by an improvement of the Hummer's method based on graphene exfoliated from graphite using high-intensity ultrasonication, resulting in two dimensional sheets with a lateral dimension in the range 200 nm to 3 mm and thickness of 0.9 nm. Confocal Raman spectroscopy combined with multivariate analysis was used to study the interaction of GONP and living cells. It is shown that overlapping Raman bands due to GONPs and biomolecules in the cells can clearly be separated with th

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CA - Inorganic chemistry

OECD FORD branch

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Project

<a href="/en/project/GA14-05146S" target="_blank" >GA14-05146S: Study of graphene – ionic liquid interactions for preparation of polymer composites</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

RSC Advances

ISSN

2046-2069

e-ISSN

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Volume of the periodical

5

Issue of the periodical within the volume

73

Country of publishing house

GB - UNITED KINGDOM

Number of pages

11

Pages from-to

59447-59457

UT code for WoS article

000357961800060

EID of the result in the Scopus database

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