Anthracycline antibiotics derivate mitoxantrone-Destructive sorption and photocatalytic degradation

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388980%3A_____%2F18%3A00488747" target="_blank" >RIV/61388980:_____/18:00488747 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/18:10376604

Result on the web

<a href="http://dx.doi.org/10.1371/journal.pone.0193116" target="_blank" >http://dx.doi.org/10.1371/journal.pone.0193116</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1371/journal.pone.0193116" target="_blank" >10.1371/journal.pone.0193116</a>

Result language

angličtina

Original language name

Anthracycline antibiotics derivate mitoxantrone-Destructive sorption and photocatalytic degradation

Original language description

Nanostructured titanium(IV) oxide was used for the destructive adsorption and photocatalytic degradation of mitoxantrone (MTX), a cytostatic drug from the group of anthracycline antibiotics. During adsorption on atitania dioxide surface, four degradation products of MTX, mitoxantrone dicarboxylic acid, 1, 4-dihydroxy-5-((2-((2-hydroxyethyl)amino)ethyl) amino)-8-((2-(methylamino)ethyl)amino)anthracene-9, 10-dione, 1, 4-dihydroxy-5, 8-diimi-noanthracene-9, 10(5H, 8H)-dione and 1, 4-dihydroxy-5-imino-8-(methyleneamino)anthra-cene-9, 10(5H, 8H)-dione, were identified. In the case of photocatalytic degradation, only one degradation product after 15 min at m/z 472 was identified. This degradation product corresponded to mitoxantrone dicarboxylic acid, and complete mineralization was attained in one hour. Destructive adsorbent manganese(IV) oxide, MnO 2 , was used only for the destructive adsorption of MTX. Destructive adsorption occurred only for one degradation product, mitoxantrone dicarboxylic acid, against anatase TiO 2 .

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10402 - Inorganic and nuclear chemistry

Project

<a href="/en/project/TG02010049" target="_blank" >TG02010049: COMNID: Support of the transfer of the apllied research results into new products and services</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2018

Confidentiality

C - Předmět řešení projektu podléhá obchodnímu tajemství (§ 504 Občanského zákoníku), ale název projektu, cíle projektu a u ukončeného nebo zastaveného projektu zhodnocení výsledku řešení projektu (údaje P03, P04, P15, P19, P29, PN8) dodané do CEP, jsou upraveny tak, aby byly zveřejnitelné.

Name of the periodical

PLoS ONE

ISSN

1932-6203

e-ISSN

—

Volume of the periodical

13

Issue of the periodical within the volume

3

Country of publishing house

US - UNITED STATES

Number of pages

15

Pages from-to

—

UT code for WoS article

000427253500005

EID of the result in the Scopus database

2-s2.0-85043765456