Convenient Synthesis of (R)-3-[(tert-Butoxycarbonyl)amino]-piperidine and (R)-3-[(tertButoxycarbonyl)amino]azepane

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388980%3A_____%2F21%3A00544130" target="_blank" >RIV/61388980:_____/21:00544130 - isvavai.cz</a>

Result on the web

<a href="https://doi.org/10.1055/a-1526-7657" target="_blank" >https://doi.org/10.1055/a-1526-7657</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1055/a-1526-7657" target="_blank" >10.1055/a-1526-7657</a>

Result language

angličtina

Original language name

Convenient Synthesis of (R)-3-[(tert-Butoxycarbonyl)amino]-piperidine and (R)-3-[(tertButoxycarbonyl)amino]azepane

Original language description

(R)-3-[(tert-Butoxycarbonyl)amino]piperidine and (R)-3-[(tert-butoxycarbonyl)amino]azepane were prepared in two steps starting from D-ornithine and D-lysine, respectively. In the key step, N-Boc-protected 3-aminolactams were converted into imido esters by O-alkylation and then hydrogenated to amines, under mild conditions (5 bar H-2, room temperature) and without isolation, over a standard hydrogenation catalyst (5% Pt/C).

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10402 - Inorganic and nuclear chemistry

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Synthesis

ISSN

0039-7881

e-ISSN

1437-210X

Volume of the periodical

53

Issue of the periodical within the volume

19

Country of publishing house

DE - GERMANY

Number of pages

5

Pages from-to

3573-3577

UT code for WoS article

000672919100001

EID of the result in the Scopus database

2-s2.0-85110430805