Low-dimensional compounds containing bioactive ligands. nPart XX: crystal structures, cytotoxic, antimicrobial activities and DNA/BSA binding of oligonuclear zinc complexes with halogen derivatives of 8-hydroxyquinoline
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388980%3A_____%2F23%3A00570239" target="_blank" >RIV/61388980:_____/23:00570239 - isvavai.cz</a>
Alternative codes found
RIV/68378271:_____/23:00570239
Result on the web
<a href="https://hdl.handle.net/11104/0342052" target="_blank" >https://hdl.handle.net/11104/0342052</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/inorganics11020060" target="_blank" >10.3390/inorganics11020060</a>
Alternative languages
Result language
angličtina
Original language name
Low-dimensional compounds containing bioactive ligands. nPart XX: crystal structures, cytotoxic, antimicrobial activities and DNA/BSA binding of oligonuclear zinc complexes with halogen derivatives of 8-hydroxyquinoline
Original language description
Two tetranuclear [Zn4Cl2(ClQ)6]2DMF and [Zn4Cl2(ClQ)6(H2O)2]4DMF, as well as three dinuclear [Zn2(ClQ)3(HClQ)3]I3, [Zn2(dClQ)2(H2O)6(SO4)] and [Zn2(dBrQ)2(H2O)6(SO4)], complexes (HClQ = 5-chloro-8-hydroxyquinoline, HdClQ = 5,7-dichloro-8-hydroxyquinoline and HdBrQ = 5,7-dibromo-8-hydroxyquinoline) were prepared as possible anticancer or antimicrobial agents and characterized by IR spectroscopy, elemental analysis and single crystal X-ray structure analysis. The stability of the complexes in solution was verified by NMR spectroscopy. Antiproliferative activity and selectivity of the prepared com plexes were studied using in vitro MTT assay against the HeLa, A549, MCF-7, MDA-MB-231, HCT116 and Caco-2 cancer cell lines and on the Cos-7 non-cancerous cell line.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10402 - Inorganic and nuclear chemistry
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Inorganic
ISSN
2304-6740
e-ISSN
2304-6740
Volume of the periodical
11
Issue of the periodical within the volume
2
Country of publishing house
CH - SWITZERLAND
Number of pages
24
Pages from-to
60
UT code for WoS article
000939265300001
EID of the result in the Scopus database
2-s2.0-85148747858