Monitoring of the dissolution/precipitation behavior of bioglass with simulated body fluid buffered by HEPES

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388980%3A_____%2F25%3A00602231" target="_blank" >RIV/61388980:_____/25:00602231 - isvavai.cz</a>

Alternative codes found

RIV/60461373:22310/25:43930233

Result on the web

<a href="https://hdl.handle.net/11104/0360773" target="_blank" >https://hdl.handle.net/11104/0360773</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1039/d4ma00752b" target="_blank" >10.1039/d4ma00752b</a>

Result language

angličtina

Original language name

Monitoring of the dissolution/precipitation behavior of bioglass with simulated body fluid buffered by HEPES

Original language description

This research work investigates a 7-day interaction of bioactive glass in the form of grit with simulated body fluid with addition of HEPES buffer (SBF+H). The standard fluid buffered by TRIS (SBF+T) and unbuffered (SBF-& Oslash,) were used for comparison. To understand the process more precisely, the material and the leachates were analyzed at hourly (1H, 2H, 4H) and daily (1D, 2D, 3D, 4D, 7D) intervals. During the static in vitro test the weight and specific surface area of the materials were measured and the surface and volume changes of the material character/composition were monitored by SEM/EDS and XRD. Samples of solution leachates were collected at regular intervals to determine concentrations of calcium, silicon and (PO4)3- and to measure pH. After exposure in SBF+T and SBF+H a new crystalline layer of hydroxyapatite formed on the material surface. The material exposed to SBF+H dissolved less than the one exposed to SBF+T but the hydroxyapatite layer on its surface grew faster. The material exposed only to SBF-& Oslash, without any buffer dissolved much less, while the ions released into the solution very rapidly re-precipitated on the surface. As a result, three amorphous layers containing Si, Ca and P with different thicknesses were gradually formed on the surface. Results of material and solution analyses have clearly shown that both HEPES and TRIS buffers have a significant effect on the formation of hydroxyapatite on the surface of bioactive glass. The behavior of the HEPES buffer with highly bioactive bioglass is very similar to that of the TRIS buffer.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10402 - Inorganic and nuclear chemistry

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Materials Advances

ISSN

2633-5409

e-ISSN

2633-5409

Volume of the periodical

6

Issue of the periodical within the volume

1

Country of publishing house

GB - UNITED KINGDOM

Number of pages

10

Pages from-to

214-223

UT code for WoS article

001365168400001

EID of the result in the Scopus database

2-s2.0-85210755894