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Fibroblasts adhesion on ion beam modified

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389005%3A_____%2F04%3A00101872" target="_blank" >RIV/61389005:_____/04:00101872 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Fibroblasts adhesion on ion beam modified

  • Original language description

    Polyethylene (PE) was irradiated with 15 keV O+, P+ and Ar+ ions to the fluences from 3 x 10(12) to 1 X 10(15) cm(-2). The changes of surface structure and polarity and oxygen concentration were examined on pristine and as-irradiated PE. The in vitro adhesion of rat 3T3 fibroblasts on the modified PE was evaluated 24 h after inoculation. Degradation of PE is manifested by the creation of conjugated double bonds and oxidation of the PE main chain. It was proved that the implanted P atoms are chemically bound onto degraded polymer chain. Wettability of the polymer surface is affected by the structure and composition of the modified surface layer. In comparison with pristine PE (i) higher cell adhesion is observed on implanted PE and (ii) the cells cultivated on implanted PE are larger and their adherence is significantly more homogeneous. The enhancement of 3T3 cells adhesion is highest and smallest for PE implanted with O+ and Ar+ ions, respectively. Highest cell adhesion was observe...

  • Czech name

    Adhese fibroblastů na polyethylenu modifikovaném iontovou implatací

  • Czech description

    Polyethylen (PE) byl ozářen ionty O, P a Ar s energií 15 keV a povrch implantovaného PE byl vyšetřován různými metodami. Adhese myších 3T3 fibroblastů na modifikovaném PE byla studována in vitro. Ve srovnání s neozářenými PE byla na ozářených vzorcích pozorována zvýšená adhese buněk. Buňky jsou rovněž větší a lépe rozprostřené.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    BG - Nuclear, atomic and molecular physics, accelerators

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA106%2F03%2F0514" target="_blank" >GA106/03/0514: Modified polymers for tissue engineering</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2004

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH

  • ISSN

    0168-583X

  • e-ISSN

  • Volume of the periodical

    215

  • Issue of the periodical within the volume

    3/4

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    7

  • Pages from-to

    366-372

  • UT code for WoS article

  • EID of the result in the Scopus database