Fibroblasts adhesion on ion beam modified
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389005%3A_____%2F04%3A00101872" target="_blank" >RIV/61389005:_____/04:00101872 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Fibroblasts adhesion on ion beam modified
Original language description
Polyethylene (PE) was irradiated with 15 keV O+, P+ and Ar+ ions to the fluences from 3 x 10(12) to 1 X 10(15) cm(-2). The changes of surface structure and polarity and oxygen concentration were examined on pristine and as-irradiated PE. The in vitro adhesion of rat 3T3 fibroblasts on the modified PE was evaluated 24 h after inoculation. Degradation of PE is manifested by the creation of conjugated double bonds and oxidation of the PE main chain. It was proved that the implanted P atoms are chemically bound onto degraded polymer chain. Wettability of the polymer surface is affected by the structure and composition of the modified surface layer. In comparison with pristine PE (i) higher cell adhesion is observed on implanted PE and (ii) the cells cultivated on implanted PE are larger and their adherence is significantly more homogeneous. The enhancement of 3T3 cells adhesion is highest and smallest for PE implanted with O+ and Ar+ ions, respectively. Highest cell adhesion was observe...
Czech name
Adhese fibroblastů na polyethylenu modifikovaném iontovou implatací
Czech description
Polyethylen (PE) byl ozářen ionty O, P a Ar s energií 15 keV a povrch implantovaného PE byl vyšetřován různými metodami. Adhese myších 3T3 fibroblastů na modifikovaném PE byla studována in vitro. Ve srovnání s neozářenými PE byla na ozářených vzorcích pozorována zvýšená adhese buněk. Buňky jsou rovněž větší a lépe rozprostřené.
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
BG - Nuclear, atomic and molecular physics, accelerators
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA106%2F03%2F0514" target="_blank" >GA106/03/0514: Modified polymers for tissue engineering</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2004
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH
ISSN
0168-583X
e-ISSN
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Volume of the periodical
215
Issue of the periodical within the volume
3/4
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
7
Pages from-to
366-372
UT code for WoS article
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EID of the result in the Scopus database
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