Progress in forensic bone DNA analysis: Lessons learned from ancient DNA

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389005%3A_____%2F21%3A00545309" target="_blank" >RIV/61389005:_____/21:00545309 - isvavai.cz</a>
Alternative codes found
RIV/00064211:_____/21:W0000014 RIV/00216208:11130/21:10429283 RIV/00216208:11310/21:10429283
Result on the web
<a href="https://doi.org/10.1016/j.fsigen.2021.102538" target="_blank" >https://doi.org/10.1016/j.fsigen.2021.102538</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.fsigen.2021.102538" target="_blank" >10.1016/j.fsigen.2021.102538</a>

Result language
angličtina
Original language name
Progress in forensic bone DNA analysis: Lessons learned from ancient DNA
Original language description
Research on ancient and forensic DNA is related in many ways, and the two fields must deal with similar ob-stacles. Therefore, communication between these two communities has the potential to improve results in both research fields. Here, we present the insights gained in the ancient DNA community with regard to analyzing DNA from aged skeletal material and the potential use of the developed protocols in forensic work. We discuss the various steps, from choosing samples for DNA extraction to deciding between classical PCR amplification and massively parallel sequencing approaches. Based on the progress made in ancient DNA analyses combined with the requirements of forensic work, we suggest that there is substantial potential for incorporating ancient DNA approaches into forensic protocols, a process that has already begun to a considerable extent. However, taking full advantage of the experiences gained from ancient DNA work will require comparative studies by the forensic DNA community to tailor the methods developed for ancient samples to the specific needs of forensic studies and case work. If successful, in our view, the benefits for both communities would be considerable.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10603 - Genetics and heredity (medical genetics to be 3)

Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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