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Macroporous hydrogels based on 2-hydroxyethyl methacrylate. Part 3. Hydrogels as carriers for immobilization of proteins

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F05%3A00023379" target="_blank" >RIV/61389013:_____/05:00023379 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Macroporous hydrogels based on 2-hydroxyethyl methacrylate. Part 3. Hydrogels as carriers for immobilization of proteins

  • Original language description

    Four series of macroporous hydrogels based on crosslinked copolymers 2-hydroxyethyl methacrylate (HEMA) ? co - sodium methacrylate (MANa), copolymer HEMA ? co - [2-(methacryloyloxy)ethyl]trimethylammonium chloride (MOETACl), terpolymer HEMA?MANa?MOETACland on their polyelectrolyte complex were used as carriers for immobilization of model proteins, albumin and avidin. The adsorption capacity of the hydrogels for the two proteins, kinetics and pH dependence of albumin adsorption and desorption were studied. The morphology of the hydrogels with and without immobilized proteins was studied by low-vacuum scanning electron microscopy.

  • Czech name

    Makroporézní hydrogely odvozené od 2-hydroxyethyl methakrylátu. Část III. Hydrogely jako nosiče k imobilizaci proteinů

  • Czech description

    Čtyři série makroporézních hydrogelů založených na síťovaných kopolymerech 2-hydroxyethylmethakrylát (HEMA) - co - methakrylát sodný (MANa), HEMA - co- [2-(methakryloyloxy)ethyl]trimethylamonium chlorid (MOETACl), terpolymeru HEMA-MANa-MOETACl a na jejich polyelektrolytovém komplexu byly použity jako nosiče pro imobilizaci modelových proteinů albuminu a avidinu. Byly studovány adsorpční kapacita hydrogelů pro oba proteiny, kinetiky adsorpce a desorpce a jejich závislost na pH. Morfologie hydrogelů předa po imobilizaci proteinů byla studována elektronovou mikroskopií za sníženého tlaku.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CD - Macromolecular chemistry

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2005

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Materials Science - Materials in Medicine

  • ISSN

    0957-4530

  • e-ISSN

  • Volume of the periodical

    16

  • Issue of the periodical within the volume

    8

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    4

  • Pages from-to

    783-786

  • UT code for WoS article

  • EID of the result in the Scopus database