All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

Use of synthetic vectors for neutralising antibody resistant delivery of replicating adenovirus DNA

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F06%3A00047074" target="_blank" >RIV/61389013:_____/06:00047074 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Use of synthetic vectors for neutralising antibody resistant delivery of replicating adenovirus DNA

  • Original language description

    Use of synthetic vectors to deliver genomes of conditionally replicating lytic viruses combines the strengths of viral and non-viral approaches by enabling neutralising antibody resistant deployment of cancer virotherapy. Adenovirus is particularly suitable for this application since all proteins essential for replication can be expressed from the input DNA, although the presence of terminal protein (TP) covalently linked to the 5' termini of the input virus genomes both improves expression of transgenes encoded in the input DNA and also enhances replication.

  • Czech name

    Použití syntetických vektorů pro dopravu replikující adenovirové DNA resistentní k neutralizující protilátce

  • Czech description

    Použití syntetických vektorů pro dopravu geonomů podmíněně se replikujících se virů kombinuje výhody virálních i nevirálních přístupů, a to využití resistence k neutralizující protilátce v nádorové genové terapii.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CD - Macromolecular chemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/KSK4055109" target="_blank" >KSK4055109: Physics, chemistry and informatics for biological, ecological and medicinal applications</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2006

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Gene Therapy

  • ISSN

    0969-7128

  • e-ISSN

  • Volume of the periodical

    13

  • Issue of the periodical within the volume

    22

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    8

  • Pages from-to

    1579-1586

  • UT code for WoS article

  • EID of the result in the Scopus database