Thermoresponsive micelles for radionuclide delivery
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F10%3A00342223" target="_blank" >RIV/61389013:_____/10:00342223 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Thermoresponsive micelles for radionuclide delivery
Original language description
We have synthesized and characterized a thermoresponsive micellar radionuclide delivery systems based on ABA triblock copolymers poly[2-methyl-2-oxazoline - block - (2-isopropyl-2-oxazoline - co - 2-butyl-2-oxazoline) - block - 2-methyl-2-oxazoline]. These polymers are molecularly dissolved in aqueous millieu below cloud point temperature (CPT) of the thermoresponsive central block and above its CPT they form polymer micelles with diameter 200 nm. A phenolic moiety introduced into the copolymer allowedradionuclide labeling with 125I ongoing in good yield with sufficient in vitro stability under model conditions.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
Abstract Book
ISBN
978-90-365-3007-1
ISSN
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e-ISSN
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Number of pages
3
Pages from-to
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Publisher name
University of Twente
Place of publication
Egmond aan Zee
Event location
Egmond aan Zee
Event date
Apr 7, 2010
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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