Polymeric nanomedicines for image-guided drug delivery and tumor-targeted combination therapy

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F10%3A00343927" target="_blank" >RIV/61389013:_____/10:00343927 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Polymeric nanomedicines for image-guided drug delivery and tumor-targeted combination therapy

Original language description

Nanomedicine systems aim to improve the biodistribution and the target site accumulation of systemically applied (chemo-) therapeutics. By increasing drug localization at the pathological site, and by reducing its accumulation in healthy organs and tissues, the efficacy of the intervention can often be increased, while its toxicity can be attenuated. Using HPMA copolymers as a model macromolecular nanomedicine system, and several selected examples of recently published proof-of-principle reports, we here show that besides for standard drug delivery purposes, polymeric nanomedicines can also be employed for image-guided drug delivery, as well as for tumor-targeted combination therapy.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

<a href="/en/project/1M0505" target="_blank" >1M0505: Center of targeted therapeutic drugs</a><br>

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Nano Today

ISSN

1748-0132

e-ISSN

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Volume of the periodical

5

Issue of the periodical within the volume

3

Country of publishing house

GB - UNITED KINGDOM

Number of pages

16

Pages from-to

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UT code for WoS article

000279753800009

EID of the result in the Scopus database

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