Quantification in MALDI-TOF mass spectrometry of modified polymers
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F11%3A00359037" target="_blank" >RIV/61389013:_____/11:00359037 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.aca.2011.03.019" target="_blank" >http://dx.doi.org/10.1016/j.aca.2011.03.019</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.aca.2011.03.019" target="_blank" >10.1016/j.aca.2011.03.019</a>
Alternative languages
Result language
angličtina
Original language name
Quantification in MALDI-TOF mass spectrometry of modified polymers
Original language description
MALDI-TOF MS quantification is hampered by the poor reproducibility and molecular-mass and compositional discrimination. The use of an internal standard increases reproducibility and allows a calibration curve to be constructed. With synthetic polymers,the method requires a polymer of the same molecular mass distribution and composition as the analyte. When the content of the precursor polymer in a modified polymer is sought, the pure precursor is usually available and the modified polymer can serve asan internal standard. The method has to be combined with that of standard addition and the precursor polymer added directly to the sample. The experiments with simulated modified polymers revealed the signal-intensity ratio not proportional to the concentrations ratio. Thus, the basic assumption of the standard-addition method is not met. Therefore, the multi-point combined internal-standard standard-addition method based on the power-type calibration curve was developed and verified.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA203%2F08%2F0543" target="_blank" >GA203/08/0543: Hybrid macromolecular systems based on hydrophilic polymers and stimuli-responsive peptides</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Analytica Chimica Acta
ISSN
0003-2670
e-ISSN
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Volume of the periodical
693
Issue of the periodical within the volume
1
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
7
Pages from-to
82-88
UT code for WoS article
000290886800010
EID of the result in the Scopus database
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