Surface-initiated polymerization of 2-hydroxyethyl methacrylate from heterotelechelic oligoperoxide-coated .gamma.-Fe2O3 nanoparticles and their engulfment by mammalian cells
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F11%3A00359776" target="_blank" >RIV/61389013:_____/11:00359776 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1021/cm2004215" target="_blank" >http://dx.doi.org/10.1021/cm2004215</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/cm2004215" target="_blank" >10.1021/cm2004215</a>
Alternative languages
Result language
angličtina
Original language name
Surface-initiated polymerization of 2-hydroxyethyl methacrylate from heterotelechelic oligoperoxide-coated .gamma.-Fe2O3 nanoparticles and their engulfment by mammalian cells
Original language description
Poly(N-vinylpyrrolidone) (CPA-PVP-IBMB) containing carboxyl from 4-cyanopentanoic acid (CPA) and peroxide from 1-isopropyl-3(4)-[1-(tert-butyl peroxy)-1-methylethyl]benzene (IBMB) chain transfer agent was synthesized as a surface-active macroinitiator for tailored functionalization of ?-Fe2O3. CPA-PVP-IBMB initiated polymerization of 2-hydroxyethyl methacrylate (HEMA) yielding CPA-PVP-block-poly(2-hydroxyethyl methacrylate) (CPA-PVP-block-PHEMA). ?-Fe2O3 obtained by precipitation was modified by CPA-PVP-IBMB and CPA-PVP-block-PHEMA by ?grafting-to using carboxyl groups. ?Grafting-from consisted in polymerization of HEMA initiated from surface of CPA-PVP-IBMB-coated ?-Fe2O3 yielding CPA-PVP-IBMB-coated ?-Fe2O3/PHEMA nanoparticles. Tests with mice leukemia L1210 cells confirmed nontoxicity of CPA-PVP-IBMB-coated ?-Fe2O3/PHEMA. CPA-PVP-IBMB-coated ?-Fe2O3/PHEMA nanoparticles were engulfed by murine macrophages J774.2 and magnetically separated from other cells.
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CD - Macromolecular chemistry
OECD FORD branch
—
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Chemistry of Materials
ISSN
0897-4756
e-ISSN
—
Volume of the periodical
23
Issue of the periodical within the volume
10
Country of publishing house
US - UNITED STATES
Number of pages
13
Pages from-to
2637-2649
UT code for WoS article
000290594700020
EID of the result in the Scopus database
—