Nonfouling poly(ethylene oxide) layers end-tethered to polydopamine
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F12%3A00381352" target="_blank" >RIV/61389013:_____/12:00381352 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1021/la3029935" target="_blank" >http://dx.doi.org/10.1021/la3029935</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/la3029935" target="_blank" >10.1021/la3029935</a>
Alternative languages
Result language
angličtina
Original language name
Nonfouling poly(ethylene oxide) layers end-tethered to polydopamine
Original language description
Nonfouling surfaces capable of reducing protein adsorption are highly desirable in a wide range of applications. Coating of surfaces with poly(ethylene oxide) (PEO), a water-soluble, nontoxic, and nonimmunogenic polymer, is most frequently used to reducenonspecific protein adsorption. Here we show how to prepare dense PEO brushes on virtually any substrate by tethering PEO to polydopamine (PDA)-modified surfaces. The chain lengths of hetero-bifunctional PEOs were varied in the range of 45?500 oxyethylene units (Mn = 2000?20?000). End-tethering of PEO chains was performed through amine and thiol headgroups from reactive polymer melts to minimize excluded volume effects. Surface plasmon resonance (SPR) was applied to investigate the adsorption of modelprotein solutions and complex biologic medium (human blood plasma) to the densely packed PEO brushes. The level of protein adsorption of human serum albumin and fibrinogen solutions was below the detection limit of the SPR measurements fo
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CD - Macromolecular chemistry
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Langmuir
ISSN
0743-7463
e-ISSN
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Volume of the periodical
28
Issue of the periodical within the volume
40
Country of publishing house
US - UNITED STATES
Number of pages
11
Pages from-to
14273-14283
UT code for WoS article
000309505000018
EID of the result in the Scopus database
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