PEG-modified magnetic hypercrosslinked poly(styrene-co-divinylbenzene) microspheres to minimize sorption of serum proteins
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F13%3A00392996" target="_blank" >RIV/61389013:_____/13:00392996 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.reactfunctpolym.2013.05.011" target="_blank" >http://dx.doi.org/10.1016/j.reactfunctpolym.2013.05.011</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.reactfunctpolym.2013.05.011" target="_blank" >10.1016/j.reactfunctpolym.2013.05.011</a>
Alternative languages
Result language
angličtina
Original language name
PEG-modified magnetic hypercrosslinked poly(styrene-co-divinylbenzene) microspheres to minimize sorption of serum proteins
Original language description
Monodisperse poly(styrene-co-divinylbenzene) [P(St-DVB)] microspheres were prepared by the precipitation polymerization of styrene (St) and divinylbenzene (DVB) in acetonitrile (ACN). Effect of St/DVB ratio and monomer concentration on morphology and particle size was investigated. Monodisperse 4.1 m P(St-DVB) microspheres were chloromethylated with chloromethyl methyl ether (CMME) and hypercrosslinked using anhydrous FeCl3 as a catalyst to form a very fine porous structure and to introduce reactive chloromethyl groups in the resulting product denoted as HC-P(St-DVB) particles. The hypercrosslinked microspheres were then functionalized with amino groups to yield HC-P(St-DVB)-NH2 particles and iron oxide was precipitated within their pores. The obtainedmicroparticles were highly magnetic with iron content 38 wt% Fe. The surface of the magnetic microspheres was newly hydrophilized with methoxy-poly(ethylene glycol) (methoxy-PEG) which was confirmed by ATR FT-IR spectroscopy. The poly(et
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CD - Macromolecular chemistry
OECD FORD branch
—
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Reactive and Functional Polymers
ISSN
1381-5148
e-ISSN
—
Volume of the periodical
73
Issue of the periodical within the volume
8
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
8
Pages from-to
1122-1129
UT code for WoS article
000322101400017
EID of the result in the Scopus database
—