Synthesis, characterization and antibacterial activity of new fluorescent chitosan derivatives
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F14%3A00425265" target="_blank" >RIV/61389013:_____/14:00425265 - isvavai.cz</a>
Alternative codes found
RIV/00216275:25310/14:39898250 RIV/00216305:26620/14:PU107463
Result on the web
<a href="http://dx.doi.org/10.1016/j.ijbiomac.2014.01.050" target="_blank" >http://dx.doi.org/10.1016/j.ijbiomac.2014.01.050</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.ijbiomac.2014.01.050" target="_blank" >10.1016/j.ijbiomac.2014.01.050</a>
Alternative languages
Result language
angličtina
Original language name
Synthesis, characterization and antibacterial activity of new fluorescent chitosan derivatives
Original language description
The present work aims to the development of innovative new derivatives of chitosan that can be used for medical applications. This innovation is based on the synthesis and characterization of chitosan-g-aminoanthracene derivatives. Thus, N-(anthracen-9-yl)-4,6-dichloro-[1,3,5]-triazin-2-amine (AT) reacted with chitosan by the following steps: at first, cyanuric chloride reacted with 9-aminoanthracene to obtain N-(anthracen-9-yl)-4,6-dichloro-[1,3,5]-triazin-2-amine (AT), then the AT reacted with chitosan to obtain (CH-g-AT). The final product of CH-g-AT was separated, purified and re-crystallized by dioxane. The structure of the prepared chitosan derivatives was confirmed by FTIR-ATR, solid-NMR, TGA, X-RD, and DSC. The new chitosan derivatives showed fluorescence spectra in liquid and in solid state as well. CH-g-AT showed also high antibacterial activity against gram ve species (Escherichia coli).
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CD - Macromolecular chemistry
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International Journal of Biological Macromolecules
ISSN
0141-8130
e-ISSN
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Volume of the periodical
65
Issue of the periodical within the volume
April
Country of publishing house
GB - UNITED KINGDOM
Number of pages
7
Pages from-to
234-240
UT code for WoS article
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EID of the result in the Scopus database
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