Water soluble poly(styrene sulfonate)-b-poly(vinylidene fluoride)-b-poly(styrene sulfonate) triblock copolymer nanoparticles
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F16%3A00460137" target="_blank" >RIV/61389013:_____/16:00460137 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1039/C6RA10241G" target="_blank" >http://dx.doi.org/10.1039/C6RA10241G</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/C6RA10241G" target="_blank" >10.1039/C6RA10241G</a>
Alternative languages
Result language
angličtina
Original language name
Water soluble poly(styrene sulfonate)-b-poly(vinylidene fluoride)-b-poly(styrene sulfonate) triblock copolymer nanoparticles
Original language description
A visible light, Mn2(CO)2-photomediated process was used to enable the iodine degenerative transfer controlled radical polymerization of vinylidene fluoride (VDF) initiated from I–(CF2)6–I, and the successive quantitative activation of the similar to CH2–CF2–I and silimar to CF2–CH2–I chain ends of I–PVDF–I, to produce a series of PNpSS-b-PVDF-b-PNpSS triblock copolymers (NpSS/VDF/NpSS = 4/60/4, 15/60/15, 34/60/34) with neopentyl styrene sulfonate (NpSS), which upon NaN3 deprotection, afforded the corresponding PNaSS-b-PVDF-b-PNaSS. All blocks, as well as PVDF, PNpSS and PNaSS formed water stable dispersion/solutions following either nanoprecipitation from acetone (PVDF, PNpSS, and PNpSS-b-PVDF-b-PNpSS) or direct dissolution in water (PNaSS, PNaSS-b-PVDF-b-PNaSS). Remarkably, all PNaSS-b-PVDF-b-PNaSS triblocks also provided indefinitely stable systems even under the high ionic strength conditions of phosphate buffered saline (PBS) solutions, corresponding to cell-isotonic, pH = 7.4 conditions. These trends were found to be consistent with the block composition dependence of the apparent hydrodynamic radius (Rh), conductivity, and zeta potential (ζ), where Rh increases upon deprotection from about 35–25 nm to about 168–136 nm in water, and decreases to 133–86 nm in PBS solutions, ζ decreases from similar to 40 mV to similar to 70 mV in water and increases to similar to 18 mV in PBS, and where the conductivity is negligible for PNpSS-b-PVDF-b-PNpSS but then increases linearly to similar to similar to 0.2 mS cm1 for PNaSS-b-PVDF-b-PNaSS in water to reach similar to 17 mS cm1 in PBS. Finally, the blocks were evaluated as promising 19F-MRI contrast agents.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CD - Macromolecular chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/LH14038" target="_blank" >LH14038: Fluorinated polymer systems for fuel cell applications</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
RSC Advances
ISSN
2046-2069
e-ISSN
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Volume of the periodical
6
Issue of the periodical within the volume
60
Country of publishing house
GB - UNITED KINGDOM
Number of pages
8
Pages from-to
55374-55381
UT code for WoS article
000378274800089
EID of the result in the Scopus database
2-s2.0-84974605050