Photoluminescent polysaccharide-coated germanium(IV) oxide nanoparticles

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F16%3A00460527" target="_blank" >RIV/61389013:_____/16:00460527 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/s00396-016-3882-y" target="_blank" >http://dx.doi.org/10.1007/s00396-016-3882-y</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00396-016-3882-y" target="_blank" >10.1007/s00396-016-3882-y</a>

Result language
angličtina
Original language name
Photoluminescent polysaccharide-coated germanium(IV) oxide nanoparticles
Original language description
In current biomedically oriented research, the development of a biomimetic nanoparticle platform is of interest to provide a molecular toolbox (i.e., allowing easy modular exchange of its parts depending on actual needs while being nontoxic and allowing real-time recognition and tracking using various methods, such as fluorescence). We report the development of germanium(IV) oxide-polysaccharide composite particles possessing these properties. The nanoparticles are based on a crystalline germanium oxide core with a size range of 20–30 and 300–900 nm. Two new simple coating techniques were compared for the preparation of the photoluminescent polysaccharide-coated germanium(IV) oxide nanoparticles. The germanium(IV)-based core allows for in situ polysaccharide attachment via direct chelation. In addition, the nanoparticles were coated with thin layer of silicon oxide. After coating, 3-(triethoxysilyl)propyl isocyanate was grafted onto the surface, and the polysaccharides were immobilized on the particle surface via a covalent urethane linkage, which allows for an even more stable polysaccharide coating than that obtained via chelation. This approach provides access to a new material platform for biological track and image applications.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CD - Macromolecular chemistry
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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