Striking effect of polymer end-group on C60 nanoparticle formation by high shear vibrational milling with alkyne-functionalized poly(2-oxazoline)s
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F19%3A00500763" target="_blank" >RIV/61389013:_____/19:00500763 - isvavai.cz</a>
Result on the web
<a href="https://pubs.acs.org/doi/10.1021/acsmacrolett.8b00998" target="_blank" >https://pubs.acs.org/doi/10.1021/acsmacrolett.8b00998</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/acsmacrolett.8b00998" target="_blank" >10.1021/acsmacrolett.8b00998</a>
Alternative languages
Result language
angličtina
Original language name
Striking effect of polymer end-group on C60 nanoparticle formation by high shear vibrational milling with alkyne-functionalized poly(2-oxazoline)s
Original language description
Buckminsterfullerene (C60) has a large potential for biomedical applications. However, the main challenge for the realization of its biomedical application potential is to overcome its extremely low water solubility. One approach is the coformulation with biocompatible water-soluble polymers, such as poly(2-oxazoline)s (PAOx), to form water-soluble C60 nanoparticles (NPs). However, uniform and defined NPs have only been obtained via a thin film hydration method or using cyclodextrin-functionalized PAOx. Here, we report the mechanochemical preparation of defined and stable C60:PAOx NPs by the introduction of a simple alkyne group as a polymer end-group. The presence of this alkyne bond is proven to be crucial in the mechanochemical synthesis of stable, defined sub-100 nm C60:PAOx NPs, with high C60 content up to 8.9 wt %.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10404 - Polymer science
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
ACS Macro Letters
ISSN
2161-1653
e-ISSN
—
Volume of the periodical
8
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
5
Pages from-to
172-176
UT code for WoS article
000459948600015
EID of the result in the Scopus database
2-s2.0-85060605719